The c-myc proto-oncogene is induced by mitogens and is a central regulator of cell growth and differentiation.The c-myc product, Myc, is a transcription factor that binds a multitude of genomic sites, estimated to be over 10-15% of all promoter regions.Target promoters generally pre-exist in an active or poised chromatin state that is further modif
Synthetic and Evolutionary Construction of a Chlorate-Reducing Shewanella oneidensis MR-1
ABSTRACT Despite evidence for the prevalence of horizontal gene transfer of respiratory genes, little is known about how pathways functionally integrate within new hosts.One example of a mobile respiratory metabolism is bacterial chlorate reduction, which is frequently encoded on composite transposons.This implies that the essential components of t
The ReCross dual-lumen microcatheter versatility during percutaneous coronary intervention of chronic total coronary occlusions
To the Editor, Microcatheters are essential tools to facilitate guidewire manipulation and exchange, thus enhancing the guidewire penetration force.1 The ReCross over-the-wire dual-lumen microcatheter (DLM) (IMDS, The Netherlands) is the latest evolution among DLM microcatheters.However, no data are available in the medical literature yet.From Sept
Neuromodulation of brain activation associated with addiction: A review of real-time fMRI neurofeedback studies
Real-time functional magnetic resonance imaging neurofeedback (rtfMRI-nf) has emerged in recent years as an imaging modality used to examine volitional control over targeted brain activity.rtfMRI-nf has also been applied clinically as a way to train individuals to self-regulate areas of the brain, or circuitry, involved in various disorders.One suc
Stochastic Growth Models for the Spreading of Fake News
The propagation of fake news in online social networks nowadays flexcon reverse osmosis water storage tank is becoming a critical issue.Consequently, many mathematical models have been proposed to mimic the related time evolution.In this work, we first consider a deterministic model that describes rumor propagation and can be viewed as an extended